Proper Use of This Medicine

It is very important that you read the Patient Information for abarelix before you start getting injections. You will need to sign the last page if you agree with treatment with abarelix. If you have any questions about this ask your doctor.

Abarelix is only prescribed by doctors who are part of Plenaxis[trade ] PLUS Program (Plenaxis[trade ] User Safety Program) that is run by the pharmaceutical (drug) company that makes the medicine.

Abarelix is given as an injection (shot) in your buttocks. Your doctor or nurse will give you the injection. It is important that you keep your appointment with your doctor's office when your injection is due.

You must always wait in your doctor's office for 30 minutes after getting each abarelix injection (shot). If a serious or life-threatening allergic reaction happens it is usually soon after getting an abarelix injection. Tell your doctor right away if you feel warm, faint or lightheaded or if you have chest tightness, shortness of breath, redness of your skin, or swelling of your face, eyelids, tongue, or throat These could be signs of an allergic reaction.

Abarelix is only used for treating advanced prostate cancer when a patient cannot have or refuses other treatments for prostate cancer

Dosing—The dose of abarelix will be different for different patients. The following information includes only the average doses of abarelix.

• For parenteral dosage form (injection):
  • For prostate cancer:
    • Adults —100 milligrams (mg) in the muscle (buttock) every two weeks for the first month, and then every four weeks (every 28 days).