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You are here : Healthopedia.com > Drugs & Medications > Detailed Drug Information (USP DI) > Anti-inflammatory Drugs, Nonsteroidal

Anti-inflammatory Drugs, Nonsteroidal (Systemic)

Description and Brand Names | Before Using | Proper Use | Precautions | Side Effects


Category
  • Analgesic—Diclofenac; Diflunisal; Etodolac; Fenoprofen; Floctafenine; Ibuprofen; Ketoprofen; Meclofenamate; Mefenamic Acid; Naproxen
  • Anti-inflammatory, nonsteroidal—Flurbiprofen; Indomethacin; Naproxen; Sulindac; Tenoxicam
  • Antidysmenorrheal—Diclofenac; Flurbiprofen; Ibuprofen; Indomethacin; Ketoprofen; Meclofenamate; Mefenamic Acid; Naproxen; Piroxicam
  • Antigout agent—Diclofenac; Diflunisal; Etodolac; Fenoprofen; Floctafenine; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Phenylbutazone; Piroxicam; Sulindac
  • Antipyretic—Ibuprofen; Indomethacin; Naproxen
  • Antirheumatic, nonsteroidal anti-inflammatory—Diclofenac; Diflunisal; Etodolac; Fenoprofen; Flurbiprofen; Ibuprofen; Indomethacin; Ketoprofen; Meclofenamate; Nabumetone; Naproxen; Oxaprozin; Phenylbutazone; Piroxicam; Sulindac; Tenoxicam; Tiaprofenic Acid; Tolmetin
  • Prostaglandin synthesis inhibitor, renal, Bartter's syndrome—Indomethacin
  • Vascular headache prophylactic—Fenoprofen; Ibuprofen; Indomethacin; Mefenamic Acid; Naproxen
  • Vascular headache suppressant—Diclofenac; Diflunisal; Etodolac; Fenoprofen; Floctafenine; Ibuprofen; Indomethacin; Ketoprofen; Meclofenamate; Mefenamic Acid; Naproxen
Description

Nonsteroidal anti-inflammatory drugs (also called NSAIDs) are used to relieve some symptoms caused by arthritis (rheumatism), such as inflammation, swelling, stiffness, and joint pain. However, this medicine does not cure arthritis and will help you only as long as you continue to take it.

Some of these medicines are also used to relieve other kinds of pain or to treat other painful conditions, such as:

  • gout attacks;
  • bursitis;
  • tendinitis;
  • sprains, strains, or other injuries; or
  • menstrual cramps.

Ibuprofen and naproxen are also used to reduce fever.

Meclofenamate is also used to reduce the amount of bleeding in some women who have very heavy menstrual periods.

Nonsteroidal anti-inflammatory drugs may also be used to treat other conditions as determined by your doctor.

Any nonsteroidal anti-inflammatory drug can cause side effects, especially when it is used for a long time or in large doses. Some of the side effects are painful or uncomfortable. Others can be more serious, resulting in the need for medical care and sometimes even death. If you will be taking this medicine for more than one or two months or in large amounts, you should discuss with your doctor the good that it can do as well as the risks of taking it. Also, it is a good idea to ask your doctor about other forms of treatment that might help to reduce the amount of this medicine that you take and/or the length of treatment.

One of the nonsteroidal anti-inflammatory drugs, phenylbutazone, is especially likely to cause very serious side effects. These serious side effects are more likely to occur in patients 40 years of age or older than in younger adults, and the risk becomes greater as the patient's age increases. Before you take phenylbutazone, be sure that you have discussed its use with your doctor. Also, do not use phenylbutazone to treat any painful condition other than the one for which it was prescribed by your doctor .

Although ibuprofen and naproxen may be used instead of aspirin to treat many of the same medical problems, they must not be used by people who are allergic to aspirin.

The 200-mg strength of ibuprofen and the 220-mg strength of naproxen are available without a prescription. However, your health care professional may have special instructions on the proper dose of these medicines for your medical condition.

Other nonsteroidal anti-inflammatory drugs and other strengths of ibuprofen and naproxen are available only with your medical doctor's or dentist's prescription. These medicines are available in the following dosage forms:

    Oral
  • Diclofenac
    • Tablets (U.S. and Canada)
    • Delayed-release tablets (U.S. and Canada)
    • Extended-release tablets (Canada)
  • Diflunisal
    • Tablets (U.S. and Canada)
  • Etodolac
    • Capsules (U.S.)
    • Tablets (U.S.)
    • Extended-release tablets (U.S.)
  • Fenoprofen
    • Capsules (U.S. and Canada)
    • Tablets (U.S. and Canada)
  • Floctafenine
    • Tablets (Canada)
  • Flurbiprofen
    • Extended-release capsules (Canada)
    • Tablets (U.S. and Canada)
  • Ibuprofen
    • Oral suspension (U.S.)
    • Tablets (U.S. and Canada)
    • Chewable tablets (U.S.)
  • Indomethacin
    • Capsules (U.S. and Canada)
    • Extended-release capsules (U.S. and Canada)
    • Oral suspension (U.S.)
  • Ketoprofen
    • Capsules (U.S. and Canada)
    • Extended-release capsules (U.S. and Canada)
    • Tablets (U.S.)
    • Delayed-release tablets (Canada)
    • Extended-release tablets (Canada)
  • Meclofenamate
    • Capsules (U.S.)
  • Mefenamic Acid
    • Capsules (U.S. and Canada)
  • Meloxicam
    • Tablets (U.S.)
  • Nabumetone
    • Tablets (U.S. and Canada)
  • Naproxen
    • Oral suspension (U.S. and Canada)
    • Tablets (U.S. and Canada)
    • Delayed-release tablets (U.S. and Canada)
    • Extended-release tablets (U.S. and Canada)
  • Oxaprozin
    • Tablets (U.S. and Canada)
  • Phenylbutazone
    • Capsules (U.S.)
    • Tablets (U.S. and Canada)
    • Buffered tablets (Canada)
  • Piroxicam
    • Capsules (U.S. and Canada)
  • Sulindac
    • Tablets (U.S. and Canada)
  • Tenoxicam
    • Tablets (Canada)
  • Tiaprofenic Acid
    • Extended-release capsules (Canada)
    • Tablets (Canada)
  • Tolmetin
    • Capsules (U.S. and Canada)
    • Tablets (U.S. and Canada)
    Rectal
  • Diclofenac
    • Suppositories (Canada)
  • Indomethacin
    • Suppositories (U.S. and Canada)
  • Ketoprofen
    • Suppositories (Canada)
  • Naproxen
    • Suppositories (Canada)
  • Piroxicam
    • Suppositories (Canada)

Brand Names

Some commonly used brand names are:

In the U.S.—

  • Actron 9
  • Advil 7
  • Advil Caplets 7
  • Advil, Children's 7
  • Aleve 14
  • Anaprox 14
  • Anaprox DS 14
  • Ansaid 6
  • Bayer Select Ibuprofen Pain Relief Formula Caplets 7
  • Cataflam 1
  • Clinoril 18
  • Cotylbutazone 16
  • Cramp End 7
  • Daypro 15
  • Dolgesic 7
  • Dolobid 2
  • EC-Naprosyn 14
  • Excedrin IB 7
  • Excedrin IB Caplets 7
  • Feldene 17
  • Genpril 7
  • Genpril Caplets 7
  • Haltran 7
  • Ibifon 600 Caplets 7
  • Ibren 7
  • Ibu 7
  • Ibu-200 7
  • Ibu-4 7
  • Ibu-6 7
  • Ibu-8 7
  • Ibuprin 7
  • Ibuprohm 7
  • Ibuprohm Caplets 7
  • Ibu-Tab 7
  • Indocin 8
  • Indocin SR 8
  • Lodine 3
  • Lodine XL 3
  • Meclomen 10
  • Medipren 7
  • Medipren Caplets 7
  • Midol IB 7
  • Mobic 12
  • Motrin 7
  • Motrin Chewables 7
  • Motrin, Children's 7
  • Motrin, Children's Oral Drops 7
  • Motrin-IB 7
  • Motrin-IB Caplets 7
  • Motrin, Junior Strength Caplets 7
  • Nalfon 4
  • Nalfon 200 4
  • Naprelan 14
  • Naprosyn 14
  • Nuprin 7
  • Nuprin Caplets 7
  • Orudis 9
  • Orudis KT 9
  • Oruvail 9
  • Pamprin-IB 7
  • Ponstel 11
  • Q-Profen 7
  • Relafen 13
  • Rufen 7
  • Tolectin 200 21
  • Tolectin 600 21
  • Tolectin DS 21
  • Trendar 7
  • Voltaren 1

In Canada—

  • Actiprofen Caplets 7
  • Advil 7
  • Advil Caplets 7
  • Albert Tiafen 20
  • Alka Butazolidin 16
  • Anaprox 14
  • Anaprox DS 14
  • Ansaid 6
  • Apo-Diclo 1
  • Apo-Diflunisal 2
  • Apo-Flurbiprofen 6
  • Apo-Ibuprofen 7
  • Apo-Indomethacin 8
  • Apo-Keto 9
  • Apo-Keto-E 9
  • Apo-Napro-Na 14
  • Apo-Napro-Na DS 14
  • Apo-Naproxen 14
  • Apo-Phenylbutazone 16
  • Apo-Piroxicam 17
  • Apo-Sulin 18
  • Apo-Tenoxicam 19
  • Butazolidin 16
  • Clinoril 18
  • Daypro 15
  • Dolobid 2
  • Feldene 17
  • Froben 6
  • Froben SR 6
  • Idarac 5
  • Indocid 8
  • Indocid SR 8
  • Medipren Caplets 7
  • Mobiflex 19
  • Motrin 7
  • Motrin-IB 7
  • Nalfon 4
  • Naprosyn 14
  • Naprosyn-E 14
  • Naprosyn-SR 14
  • Naxen 14
  • Novo-Difenac 1
  • Novo-Difenac SR 1
  • Novo-Diflunisal 2
  • Novo-Flurprofen 6
  • Novo-Keto-EC 9
  • Novo-Methacin 8
  • Novo-Naprox 14
  • Novo-Naprox Sodium 14
  • Novo-Naprox Sodium DS 14
  • Novo-Pirocam 17
  • Novo-Profen 7
  • Novo-Sundac 18
  • Novo-Tenoxicam 19
  • Novo-Tolmetin 21
  • Nu-Diclo 1
  • Nu-Flurbiprofen 6
  • Nu-Ibuprofen 7
  • Nu-Indo 8
  • Nu-Naprox 14
  • Nu-Pirox 17
  • Orudis 9
  • Orudis-E 9
  • Orudis-SR 9
  • Oruvail 9
  • PMS-Piroxicam 17
  • Ponstan 11
  • Relafen 13
  • Rhodis 9
  • Rhodis-EC 9
  • Surgam 20
  • Surgam SR 20
  • Synflex 14
  • Synflex DS 14
  • Tolectin 200 21
  • Tolectin 400 21
  • Tolectin 600 21
  • Voltaren 1
  • Voltaren Rapide 1
  • Voltaren SR 1

Other commonly used names are: Etodolic acid Indometacin Meclofenamic acid

Note:

For quick reference, the following nonsteroidal anti-inflammatory drugs are numbered to match the corresponding brand names.
This information applies to the following medicines:
1. Diclofenac (dye-KLOE-fen-ak)
2. Diflunisal (dye-FLOO-ni-sal)‡
3. Etodolac (ee-TOE-doe-lak)†
4. Fenoprofen (fen-oh-PROE-fen)‡
5. Floctafenine (flok-ta-FEN-een)*
6. Flurbiprofen (flure-BI-proe-fen)‡§
7. Ibuprofen (eye-byoo-PROE-fen)‡§
8. Indomethacin (in-doe-METH-a-sin)‡
9. Ketoprofen (kee-toe-PROE-fen)‡
10. Meclofenamate (me-kloe-FEN-am-ate)†‡
11. Mefenamic Acid (me-fe-NAM-ik)
12. Meloxicam (mel-OX-i-cam)‡
13. Nabumetone (na-BYOO-me-tone)
14. Naproxen (na-PROX-en)‡
15. Oxaprozin (ox-a-PROE-zin)
16. Phenylbutazone (fen-ill-BYOO-ta-zone)‡
17. Piroxicam (peer-OX-i-kam)‡
18. Sulindac (sul-IN-dak)‡
19. Tenoxicam (ten-OX-i-kam)*
20. Tiaprofenic Acid (tie-a-pro-FEN-ik)*
21. Tolmetin (TOLE-met-in)‡
* Not commercially available in the U.S.
† Not commercially available in Canada
‡ Generic name product may be available in the U.S.
§ Generic name product may be available in Canada

This information does not apply to aspirin or other salicylates or to ketorolac (e.g., Toradol).

   

Next section

   

Anti-inflammatory Drugs, Nonsteroidal: Before Using

Date Revised: 02/06/2001






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Page Last Updated: 30th May, 2006