Proper Use of This Medicine

Your doctor will ask you to empty your bladder completely before the solution is instilled into it.

Follow your doctor's instructions carefully about how long to hold the solution in your bladder :

• The solution should be held in your bladder for 2 hours. If you think you cannot hold it, tell your health care professional.
• During the first hour, your doctor may have you lie for 15 minutes each on your stomach, back, and each side.
• When you do empty your bladder, you should be sitting down.

It is important that you drink extra fluids for several hours after each treatment with BCG so that you will pass more urine. Also, empty your bladder frequently. This will help prevent bladder problems.

BCG is a live product. In other words, it contains active bacteria that can cause infection. Some bacteria will be present for several hours in urine that you pass after each treatment with BCG. Any urine that you pass during the first 6 hours after each treatment should be disinfected with an equal amount (usually about 1 cup) of undiluted household bleach. After the bleach is added to the urine, it should be allowed to sit for 15 minutes before it is flushed. If you have any questions about this, check with your doctor.

Dosing—The dose of BCG will be different for different patients. The dose that is used may depend on a number of things. If you are receiving BCG at home, follow your doctor's orders or the directions on the label . If you have any questions about the proper dose of BCG, ask your doctor.