Before Using This Medicine

In deciding to use a medicine, the risks of using the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For choriogonadotropin alfa, the following should be considered:

Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to choriogonadotropin alfa . Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy—Choriogonadotropin alfa is not recommended during pregnancy. Since women using choriogonadotropin alfa may be more likely to have more than one child at a time, the problems related to multiple births should be considered by women using this medicine. Also, this medicine has been shown to overstimulate the ovaries (ovarian hyperstimulation syndrome) for a longer time in some women who conceive than in women developing this syndrome who do not become pregnant. Before you use this medicine, make sure your doctor knows if you are pregnant.

Breast-feeding—It is not known whether choriogonadotropin alfa passes into breast milk. Mothers who are taking this medicine and who wish to breast-feed should discuss this with your doctor

Children—Studies on this medicine have been done only in adult patients and there is no information comparing use of choriogonadotropin alfa in children with use in other age groups.

Older adults—Many medicines have not been studied specifically in older people. Therefore it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of choriogonadotropin alfa in the elderly with use in other age groups.

Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Other medical problems—The presence of other medical problems may affect the use of choriogonadotropin alfa. Make sure you tell your doctor if you have any other medical problems, especially:

• Abnormal bleeding of uterus (unknown cause)
• Adrenal gland or thyroid disease (not controlled)
• Tumor, brain or sex-dependent
• Ovarian cyst or enlarged ovaries (unknown cause)
• Primary ovarian failure