Precautions While Using This Medicine

Misoprostol may cause miscarriage if taken during pregnancy. Therefore, if you suspect that you may have become pregnant, stop taking this medicine immediately and check with your doctor .

This medicine may cause diarrhea in some people. The diarrhea will usually disappear within a few days as your body adjusts to the medicine. However, check with your doctor if the diarrhea is severe and/or does not stop after a week.

If you will be taking this medicine for a long time, your doctor should check your progress at regular visits. Your doctor may want to do certain tests to find out if unwanted effects are occurring. The tests are very important because serious side effects, including ulcers, bleeding, blood, or liver problems, can occur without any warning.

Stomach problems may be more likely to occur if you drink alcoholic beverages while being treated with this medicine. Therefore, do not regularly drink alcoholic beverages while taking this medicine, unless otherwise directed by your doctor.

Taking nonsteroidal anti-inflammatory drugs together with this medicine on a regular basis may increase the chance of unwanted effects. Also, taking acetaminophen, aspirin or other salicylates, or ketorolac (e.g.,Toradol) regularly while you are taking a diclofenac and misoprostol combination may increase the chance of unwanted effects. The risk will depend on how much of each medicine you take every day, and on how long you take the medicine together. If your health care professional directs you to take these medicines together on a regular basis, follow his or her directions carefully. However, do not take acetaminophen or aspirin or other salicylates together with this medicine for more than a few days, and do not take any ketorolac (e.g., Toradol) while you are taking this medicine, unless your doctor has directed you to do so and is following your progress.