Proper Use of This Medicine

Hepatitis B immune globulin (human) is given as a shot into the muscle of the upper arm, upper thigh, or outer area of the buttocks.

Dosing—The dose of hepatitis B immune globulin (human) will be different for different patients. The following information includes only the average doses of hepatitis B immune globulin.

• For injectable dosage form:
  • For prevention of hepatitis B following nonsexual exposure:
    • Adults—Dose is based on weight and will be determined by your doctor. If you have never been vaccinated with hepatitis B virus vaccine, your doctor may start the vaccination series. If you have been vaccinated, you may need a booster.
    • Infants with mothers who test positive for hepatitis B—Dose is usually 0.5 milliliters (mL) injected into a muscle in the thigh.
  • For prevention of hepatitis B following sexual exposure:
    • Adults—Dose is based on weight and will be determined by your doctor. Your doctor may start the hepatitis B virus vaccination series if the exposure has been within the last 14 days or if sexual contact is likely to continue.
  • For prevention of hepatitis B following household exposure:
    • Infants less than 12 months of age—Dose is usually 0.5 mL injected into a muscle in the thigh.