Histamine H 2-receptor Antagonists (Systemic)
Category- Histamine H 2
-receptor antagonist—Cimetidine; Famotidine; Nizatidine; Ranitidine
- Antiulcer agent—Cimetidine; Famotidine; Nizatidine; Ranitidine
- Gastric acid secretion inhibitor—Cimetidine; Famotidine; Nizatidine; Ranitidine
- Urticaria therapy
adjunct—Cimetidine
DescriptionHistamine H 2
-receptor antagonists, also known as H 2
-blockers,
are used to treat duodenal ulcers and prevent their return. They are also
used to treat gastric ulcers and for some conditions, such as Zollinger-Ellison
disease, in which the stomach produces too much acid. In over-the-counter
(OTC) strengths, these medicines are used to relieve and/or prevent heartburn,
acid indigestion, and sour stomach. H 2
-blockers
may also be used for other conditions as determined by your doctor.
H 2
-blockers work by decreasing the amount
of acid produced by the stomach.
They are available in the following dosage forms:
Oral
-
Cimetidine
-
Oral solution (U.S. and Canada)
-
Tablets (U.S. and Canada)
-
Famotidine
-
Oral suspension (U.S.)
-
Tablets (U.S. and Canada)
-
Chewable tablets (U.S. and Canada)
-
Oral disintegrating tablets (U.S.)
-
Nizatidine
-
Capsules (U.S. and Canada)
-
Tablets (U.S.)
-
Ranitidine
-
Effervescent granules (U.S.)
-
Syrup (U.S. and Canada)
-
Tablets (U.S. and Canada)
-
Effervescent tablets (U.S.)
Parenteral
-
Cimetidine
-
Injection (U.S. and Canada)
-
Famotidine
-
Injection (U.S. and Canada)
-
Ranitidine
-
Injection (U.S. and Canada)
Brand NamesSome commonly used brand names are:
In the U.S.—
- Axid 3
- Axid AR 3
- Mylanta AR Acid Reducer 2
- Pepcid 2
- Pepcid I.V. 2
- Pepcid AC Acid Controller 2
- Pepcid RPD 2
- Tagamet 1
- Tagamet HB 1
- Zantac 4
- Zantac EFFERdose Granules 4
- Zantac EFFERdose Tablets 4
In Canada—
- Acid Control 2
- Act 2
- Apo-Cimetidine 1
- Apo-Famotidine 2
- Apo-Nizatidine 3
- Apo-Ranitidine 4
- Axid 3
- Dyspep HB 2
- Gen-Cimetidine 1
- Gen-Famotidine 2
- Gen-Ranitidine 4
- Maalox H2 Acid Controller 2
- Novo-Cimetine 1
- Novo-Famotidine 2
- Novo-Ranitidine 4
- Nu-Cimet 1
- Nu-Famotidine 2
- Nu-Ranit 4
- Pepcid 2
- Pepcid AC 2
- Pepcid I.V. 2
- Peptol 1
- PMS-Cimetidine 1
- Tagamet 1
- Ulcidine 2
- Ulcidine-HB 2
- Zantac 4
- Zantac 75 4
|
Note:
|
For quick reference, the following histamine H 2-receptor
antagonists are numbered to match the corresponding brand names.
|
| This information applies to the following medicines: |
| 1. |
Cimetidine (sye-MET-i-deen)ठ|
| 2. |
Famotidine (fa-MOE-ti-deen)§ |
| 3. |
Nizatidine (ni-ZA-ti-deen) |
| 4. |
Ranitidine (ra-NIT-ti-deen)‡ |
| ‡ Generic name product may be available
in the U.S. |
| § Generic name product may be available
in Canada |
|
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