Nitrates Oral (Systemic)
Category- Antianginal—Isosorbide
Dinitrate; Isosorbide Mononitrate; Nitroglycerin
- Vasodilator,
congestive heart failure—Isosorbide Dinitrate; Nitroglycerin
DescriptionNitrates (NYE-trates) are used to treat the symptoms
of angina (chest pain). Depending on the type of dosage form and how it is
taken, nitrates are used to treat angina in three ways:
-
to relieve an attack that is occurring by using the medicine when
the attack begins;
-
to prevent attacks from occurring by using the medicine just before
an attack is expected to occur; or
-
to reduce the number of attacks that occur by using the medicine
regularly on a long-term basis.
When taken orally and swallowed, nitrates are used to reduce the number
of angina attacks that occur. They do not act fast enough to relieve the pain
of an angina attack.
Nitrates work by relaxing blood vessels and increasing the supply of blood
and oxygen to the heart while reducing its work load.
Nitrates may also be used for other conditions as determined by your doctor.
The nitrates discussed here are available only with your doctor's prescription,
in the following dosage forms:
Oral
-
Isosorbide dinitrate
-
Extended-release capsules (U.S.)
-
Tablets (U.S. and Canada)
-
Chewable tablets (U.S.)
-
Extended-release tablets (U.S. and Canada)
-
Isosorbide mononitrate
-
Extended-release tablets (U.S.)
-
Tablets (U.S.)
-
Nitroglycerin
-
Extended-release capsules (U.S.)
-
Extended-release tablets (U.S. and Canada)
Brand NamesSome commonly used brand names are:
In the U.S.—
- Dilatrate-SR 1
- IMDUR 2
- ISDN 1
- ISMO 2
- Isordil Tembids 1
- Isordil Titradose 1
- Monoket 2
- Nitrocot 3
- Nitroglyn E-R 3
- Nitro-par 3
- Nitro-time 3
- Nitrong 3
- Sorbitrate 1
In Canada—
- Apo-ISDN 1
- Cedocard-SR 1
- Coradur 1
- Coronex 1
- IMDUR 2
- ISMO 2
- Isordil Titradose 1
- Nitrong SR 3
Another commonly used name is:
|
Note:
|
For quick reference, the following nitrates are numbered
to match the corresponding brand names.
|
| This information applies to the following medicines: |
| 1. |
Isosorbide Dinitrate (eye-soe-SOR-bide dye-NYE-trate)ठ|
| 2. |
Isosorbide Mononitrate (eye-soe-SOR-bide mon-oh-NYE-trate) |
| 3. |
Nitroglycerin (nye-troe-GLI-ser-in)‡ |
| ‡ Generic name product may be available
in the U.S. |
| § Generic name product may be available
in Canada |
|
Note:
|
This information does not
apply to amyl
nitrite or mannitol hexanitrate. |
|
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