Amphotericin B (Injection)

Amphotericin B (am-foe-TER-i-sin B)

Treats infections caused by a fungus.Belongs to a class of drugs called antifungals.

Brand Name(s):

Fungizone Intravenous, Amphocin
There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have ever had an allergic reaction to amphotericin B.

How to Use This Medicine:

Injectable

• Your doctor will prescribe your exact dose and tell you how often it should be given. Keep all medicine out of the reach of children.
• An IV infusion is medicine that is put directly into your body through one of your veins.
• This medicine should be given by a person trained to give an IV, such as a nurse. Sometimes you, a family member, or friend can be taught to give your medicine.
• Check the bag to make sure there are no leaks. Also make sure the solution is clear.

If a dose is missed:

• This medicine needs to be given on a regular schedule. Take the missed dose as soon as you remember.
• If you miss more than one dose, call your doctor for instructions.

How to Store and Dispose of This Medicine:

• Store in a refrigerator. Do not freeze. Take it out of the refrigerator an hour before the time for your next dose and allow it to warm to room temperature in a clean, dry place.
• If you see particles in the solution, You should not use it.
• If you have your treatments at home, you should be given a special container for the used needles. Keep it where children or pets cannot reach it.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Make sure your doctor knows if you are taking a diuretic (water pills), digoxin (Lanoxin®), a corticosteroid (such as prednisone or cortisone), other antifungal medicine (such as Ancobon®, Nizoral®, or Monistat®) or any antibiotic before you take this medicine.

Warnings While Using This Medicine:

• If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.
• Make sure your doctor knows if you have kidney disease.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Severe nausea and vomiting
• Shaking and chills
• Numbness or tingling in the hands or feet
• Swelling of the face, lips, or tongue
• Trouble breathing
• Swelling, pain, or redness near where the IV needle is given
• Water retention (swelling of the ankles and feet)
• Urinating less than 1 cup in a day
• Severe weakness, muscle cramps

If you notice these less serious side effects, talk with your doctor:

• Mild diarrhea
• Mild nausea or upset stomach

If you notice other side effects that you think are caused by this medicine, tell your doctor.