Fluorouracil (On The Skin)

Fluorouracil (flure-oh-YOOR-a-sil)

Treats solar keratoses (red wart-like growth on the skin), skin cancer, and tumors on the face.

Brand Name(s):

Efudex, Carac, Fluoroplex
There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have ever had an allergic reaction to fluorouracil.

How to Use This Medicine:

Cream, Liquid

• Your doctor will tell you how much medicine to take and how often.
• Use this medicine only on the skin. Do not get this medicine in your eyes, nose, or mouth.
• Wear medical gloves when putting this medicine on.
• Wash the skin to be treated with soap and water before putting this medicine on. Also wash your hands before and after using this medicine.
• Use enough cream or solution to cover the area of skin you are treating.
• Do not put a bandage over the area unless your doctor has told you to.
• You should not use fluorouracil more often or for longer periods than ordered by your doctor.

If a dose is missed:

• Use your medicine as soon as you remember that you have missed your dose.
• If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose.
• Do not put on two doses at one time.

How to Store and Dispose of This Medicine:

• Keep the medicine at room temperature, away from heat and direct light. Do not freeze.
• Keep all medicine away from children.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Do not mix fluorouracil with other skin lotions or ointments unless your doctor has told you to.

Warnings While Using This Medicine:

• If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.
• Let your doctor know about any other medical problems you have.
• If your doctor tells you to use a bandage, use a gauze bandage with tape, rather than a plastic bandage that is more likely to cause skin irritation.
• Avoid being in sunlight while using this medicine.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Severe skin rash or itching

If you notice these less serious side effects, talk with your doctor:

• Mild itching or burning
• Change in skin color where medicine is put on
• Pain where medicine is put on
• Hair loss
• Scarring, blistering, redness, or peeling of skin

If you notice other side effects that you think are caused by this medicine, tell your doctor.