Tirofiban (Injection)

Tirofiban (tye-roe-FYE-ban)

Treats chest pain and certain heart conditions, and is used during medical procedures involving the heart or arteries.

Brand Name(s):

Aggrastat
There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not receive this medicine if you have had an allergic reaction to tirofiban, or if you have severe high blood pressure, bleeding, aneurysm, certain heart conditions, or have had a stroke, surgery, or severe injury within the last 30 days. You should not receive tirofiban if you are also receiving abciximab (Reopro®) or eptifibatide (Integrilin®)

How to Use This Medicine:

Injectable

• Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.
• A nurse or other trained health professional will give you this medicine.
• This medicine is given slowly, so the needle will remain in place for several hours up to a few days.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Make sure your doctor knows if you are also using aspirin, blood thinners (Coumadin®), or any medicine for blood clots or heart disorders.

Warnings While Using This Medicine:

• Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease or are on dialysis.
• Your doctor will need to check your blood or urine at regular visits while you are using this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in face or hands, swelling or tingling in the mouth or throat, tightness in chest, trouble breathing
• Blood in your urine or stools
• Lightheadedness or fainting
• Slow heartbeat
• Sudden, severe pain in your head, neck, shoulders, or back
• Swelling in your hands, ankles, or feet
• Unusual bleeding, bruising, or weakness

If you notice these less serious side effects, talk with your doctor:

• Headache
• Increased sweating
• Nausea
• Pain in your legs or pelvis
• Redness, pain, or swelling where the IV is given

If you notice other side effects that you think are caused by this medicine, tell your doctor.