What can be done to prevent the disease?

G6PD deficiency is an inherited disease, so it cannot be prevented. Genetic counseling may be helpful to couples with a family history of the disease.

What are the long-term effects of the disease?

Some people may have a mild form of G6PD deficiency with no long-term effects. Children with severe forms of this disease may have growth problems. These children may need constant monitoring and treatment. Some long-term problems include an enlarged spleen or liver and the need for blood transfusions.

Severe, sudden attacks of G6PD deficiency can result in kidney damage, congestive heart failure, shock, and even death. This is uncommon in the variety of G6PD deficiency seen in the US. Most affected people in the US can lead a normal life if they are able to avoid the medications and illnesses that cause sudden red blood cell death.

What are the risks to others?

G6PD deficiency is not contagious, but an abnormal G6PD gene can be passed on to children, who may or may not get the disease.