Peyronie's disease is a disorder in which one or more small areas of plaque, or fibrous tissue, develop in the penis. This abnormality causes painful erections and difficulty with intercourse.

What is going on in the body?

Men with Peyronie's disease develop one or more areas of plaque on the penis. The man may experience a mild aching in a specific area of the penis well before any lump or plaque can be felt. The areas usually develop on the upper side of the penis but are sometimes found on the underside. The plaque may be painless, but the ability of the penis to become erect can be affected. The penis may be curved when erect, with resulting pain. As time goes on, the plaque may spread, causing more bending of the penis or discomfort.

What are the causes and risks of the disease?

Sometimes, Peyronie's disease is due to infection or trauma, but usually the cause is unknown. It is most common in men in their 40s to 60s, but can be seen as early as the 20s and 30s.