Staphylococcal scalded skin syndrome (SSSS) is an infection that causes inflammation and shedding, or peeling, of the skin. Bacteria called Staphylococcus aureus cause the infection.

What is going on in the body?

Certain types of staphylococcal bacteria release a toxin that causes redness and peeling of the surface skin. A mild infection with these bacteria usually starts in a small area of the skin. However, the toxin that is released can get into the bloodstream and affect skin all over the body. Staphylococcal scalded skin syndrome usually occurs in infants and young children but is sometimes seen in adults.

What are the causes and risks of the infection?

Staphylococcal scalded skin syndrome is caused by an infection with Staphylococcus aureus bacteria. Children less than 5 years old are at the highest risk. Adults with weakened immune systems and kidney failure also have a higher risk.