What are the signs and symptoms of the infection?

Primary syphilis can cause one or more painless ulcers, or sores, at the point where the bacteria entered the body. These sores are usually on the genitals. They may also be found around the anus, in the rectum or vagina, on the lips, and in the mouth.

Secondary syphilis involves a generalized rash that usually appears on the palms and soles. The usual rash appears as red spots that can be flat or raised. However, many different skin rashes can occur. Following are other symptoms of secondary syphilis:

Sometimes people can develop meningitis, which is an inflammation of the membrane lining the brain and spinal cord. Secondary syphilis may cause may cause eye, kidney, or liver problems.

Tertiary syphilis can involve any organ of the body. When the brain is involved, it is called neurosyphilis. Some of the problems neurosyphilis can cause are as follows:

People with congenital syphilis can have no symptoms or very severe symptoms. It can even cause death. As with syphilis that is acquired sexually, congenital syphilis can affect any organ in the body.

The usual symptoms of congenital syphilis include the following:

If left untreated, the late signs of congenital syphilis include subtle bone malformations, malformed teeth, and eye and brain problems.