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You are here : Healthopedia.com > Medical Encyclopedia > Diseases and Conditions > Systemic Lupus Erythematosus: Symptoms & Signs
      Category : Health Centers > Immune System

Systemic Lupus Erythematosus

Alternate Names : Lupus

Systemic Lupus Erythematosus | Symptoms & Signs | Diagnosis & Tests | Prevention & Expectations | Treatment & Monitoring | Attribution


What are the signs and symptoms of the disease?

Because SLE affects so many different parts of the body, the disease has many signs and symptoms. These are best listed by organ system.

Signs and symptoms that affect the whole body:

  • fatigue
  • fever
  • loss of appetite
  • nausea
  • weight loss
  • Signs and symptoms that affect the skin:

  • hives
  • loss of scalp hair
  • red "butterfly rash" on the face, which extends over the cheeks and bridge of the nose in the shape of a butterfly
  • red, raised rashes in areas exposed to the sun
  • sensitivity to the sun
  • ulcers of the mouth, nose, or vagina
  • Symptoms and signs that affect the muscles, bones, and joints:

  • arthritis
  • hand deformities
  • joint pain, especially in the hands, wrists, and knees
  • loss of the blood supply to bone, especially hips and shoulders
  • muscle pains and weakness
  • serious infection within a joint
  • Signs and symptoms of kidney involvement:

  • blood in the urine
  • decrease in kidney function or kidney failure
  • protein in the urine
  • white blood cells in the urine
  • Signs and symptoms affecting the nervous system:

  • bleeding in the brain, known as intracerebral hemorrhage
  • headaches, including migraines
  • loss of coordination
  • memory loss, problems with concentration
  • numbness, pain, or a feeling of "pins and needles" in the hands and feet
  • problems with the major nerves in the head and face
  • seizures
  • strokes
  • Signs and symptoms involving the blood:

  • anemia, which is a low red blood cell count
  • low blood platelet count
  • low white blood cell count
  • problems with both blood clotting and bleeding
  • Signs and symptoms involving the heart:

  • fluid collection in the sac around the heart, known as pericardial effusion
  • heart attack
  • heart valve problems
  • inflammation and infection in the heart
  • inflammation of the lining of the heart
  • Signs and symptoms involving the lungs:

  • cough, including coughing up blood
  • fluid in the lung
  • inflammation in the lung
  • inflammation of the lining of the lungs
  • shortness of breath
  • Signs and symptoms affecting the digestive system:

  • abdominal distress
  • diarrhea
  • enlargement of the liver
  • intestinal perforation due to inflammation of blood vessels
  • loss of appetite
  • nausea and vomiting
  • rectal bleeding caused by ulcerations
  • Symptoms and signs affecting the eye:

  • blindness
  • conjunctivitis, which is inflammation of the outer lining of the eye
  • damage to the retina, which may cause visual impairments

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    Systemic Lupus Erythematosus: Overview, Causes, & Risk Factors

     

    Systemic Lupus Erythematosus: Diagnosis & Tests

    Author: Minot Cleveland, MD
    Reviewer: Eileen McLaughlin, RN, BSN
    Date Reviewed: 08/06/01









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    Page Last Updated: 6th April, 2009