Zollinger-Ellison Syndrome
Alternate Names : Symptomatic Gastrinoma
What are the signs and symptoms of the condition?
Most symptoms of Zollinger-Ellison syndrome are caused by the high level of stomach acid and the ulcers that develop as a result. Symptoms include:
abdominal distress, usually located in the area between the breastbone and the navel. The distress can be sharp, burning, or gnawing pain. It can also take the form of a sensation of pressure, fullness, or hunger. The pain typically develops 30 to 90 minutes after a meal. It is often relieved by food or antacids.
heartburn, or gastroesophageal reflux, caused by stomach contents splashing back up into the esophagus. This backflow causes pain or burning in the abdomen that travels up toward the throat.
diarrhea, which may include stools that float and are foul smelling
weight loss
bleeding in the stools. This may turn the stools dark red, black or make them sticky or "tarry."
nausea and vomiting. The vomit may contain blood or may resemble coffee grounds.
A common sign of ZES is abdominal tenderness, especially in the upper abdomen.
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